DOCK1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Mouse, Rat, Zebrafish
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region within amino acids 1802 and 1865 of DOCK1
Isotype	IgG
Formulation	1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	215 kDa
Gene Name	dedicator of cytokinesis 1
Database Link	NP_001371 Entrez Gene 309081 RatEntrez Gene 330662 MouseEntrez Gene 1793 Human UniProt ID Q14185
Background	This gene product binds to the SH3 domain of CRK protein. It may regulate cell surface extension and may have a role in the cell surface extension of an engulfing cell around a dying cell during apoptosis. [provided by RefSeq]
Synonyms	ced5; DOCK180
Note	Seq homology of immunogen across species: Mouse (100%), Rat (100%), Zebrafish (92%)
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Focal adhesion, Regulation of actin cytoskeleton

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