Camk2a Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:4,000 - 1:20,000, WB: 1:1,000 - 1:3,000
Reactivity	Human, Mouse, Rat, Dog, Orang-Utan
Host	Rabbit
Clonality	Polyclonal
Immunogen	This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 6-23 of Human CaM Kinase II protein.
Isotype	IgG
Formulation	0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	calcium/calmodulin-dependent protein kinase II alpha
Database Link	NP_037052 Entrez Gene 815 HumanEntrez Gene 12322 MouseEntrez Gene 612941 DogEntrez Gene 25400 Rat UniProt ID P11275
Synonyms	CAMKA; CaMKIINalpha; KIAA0968
Note	CaM Kinase II (also known as CAMK2 and calcium/calmodulin-dependent protein kinase type II alpha chain) is a prominent kinase in the central nervous system that may function in the long-term potentiation of neurotransmitter release. CaM Kinase II autophosphorylates itself at Thr-286 which allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CaM Kinase II is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. This kinase is expressed in brain tissue. Alternative splicing occurs for this gene product.
Reference Data

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