APBA2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	APBA2 antibody was raised against an 18 amino acid synthetic peptide near the center of human APBA2.
Isotype	IgG
Formulation	APBA2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	APBA2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	amyloid beta precursor protein binding family A member 2
Database Link	NP_005494 Entrez Gene 321 Human UniProt ID Q99767
Background	APBA2 Antibody: APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer's disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer's disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.
Synonyms	D15S1518E; HsT16821; LIN-10; MGC:14091; MINT2; X11-BETA; X11L
Reference Data

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