Cripto1 (TDGF1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Rabbit polyclonal TDGF1 antibody was raised against a 17 amino acid peptide near the amino terminus of human TDGF1.
Formulation	TDGF1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	TDGF1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	21 kDa
Gene Name	teratocarcinoma-derived growth factor 1
Database Link	NP_003203 Entrez Gene 6997 Human UniProt ID P13385
Background	TDGF1 Antibody: Teratocarcinoma-derived growth factor 1 (TDGF1 or Cripto) is a member of the epidermal growth factor-cripto FRL1 cryptic protein family and is involved in the activation of several different signaling pathways during embryonic development and cellular transformation. It is first expressed in the forming mesoderm during gastrulation but later in development the expression is restricted to the truncus arteriosus of the developing heart. This suggests that TDGF1 mediates the progression of epiblastic cells that give rise to the mesoderm. TDGF1 overexpression is characteristic of human gastric and colorectal carcinomas.
Synonyms	CR; CRGF; CRIPTO
Reference Data

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