Uroplakin Ib (UPK1B) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 0.5 - 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	UPK1B antibody was raised against a 17 amino acid synthetic peptide near the center of human UPK1B.
Isotype	IgG
Formulation	UPK1B Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	UPK1B Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	uroplakin 1B
Database Link	NP_008883 Entrez Gene 22268 MouseEntrez Gene 303924 RatEntrez Gene 7348 Human UniProt ID O75841
Background	UPK1B Antibody: Uroplakin-1B (UPK1B) is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. UPK1B is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins and may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.
Synonyms	TSPAN20; UPIB; UPK1
Reference Data
Protein Families	Transmembrane

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