TFEB Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	TFEB antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human TFEB.
Formulation	TFEB Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	TFEB Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Gene Name	transcription factor EB
Database Link	NP_009093 Entrez Gene 7942 Human UniProt ID P19484
Background	TFEB Antibody: The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors. Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1. Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.
Synonyms	ALPHATFEB; BHLHE35; TCFEB
Reference Data

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