EPM2A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	EPM2A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human EPM2A.
Isotype	IgG
Formulation	EPM2A Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	EPM2A Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	36 kDa
Gene Name	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
Database Link	NP_005661 Entrez Gene 13853 MouseEntrez Gene 114005 RatEntrez Gene 7957 Human UniProt ID O95278
Background	EPM2A Antibody: The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.
Synonyms	EPM2; MELF
Reference Data
Protein Families	Druggable Genome, Phosphatase

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