IFITM1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 20 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	IFITM1 antibody was raised against a 16 amino acid synthetic peptide near the center of human IFITM1.
Isotype	IgG
Formulation	IFITM1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	IFITM1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	interferon induced transmembrane protein 1
Database Link	NP_003632 Entrez Gene 68713 MouseEntrez Gene 293618 RatEntrez Gene 8519 Human UniProt ID P13164
Background	IFITM1 Antibody: IFITM1 (Interferon inducible transmembrane protein 1) is a member of the IFN-inducible transmembrane protein family. It is an essential mediator of interferon-gamma-induced antiproliferation and plays a role in the control of cell growth. IFITM1 is upregulated in several tumor types and may be useful as a tumor biomarker. Both mouse IFITM1 and IFITM3 are expressed on the cell surfaces of primordial germ cells in a developmentally-regulated manner. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.
Synonyms	9-27; CD225; DSPA2a; IFI17; LEU13
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	B cell receptor signaling pathway

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