LCMT2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	TYW4 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human TYW4.
Isotype	IgG
Formulation	TYW4 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	TYW4 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	leucine carboxyl methyltransferase 2
Database Link	NP_055608 Entrez Gene 296098 RatEntrez Gene 329504 MouseEntrez Gene 9836 Human UniProt ID O60294
Background	TYW4 Antibody: TYW4 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW4 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.
Synonyms	PPM2; TYW4
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Alzheimer's disease, Androgen and estrogen metabolism, Cardiac muscle contraction, Histidine metabolism, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease, Selenoamino acid metabolism, Tyrosine metabolism

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