UBA2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 0.25 ug/mL, ICC:4 ug/mL, IF: 5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	SAE2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SAE2.
Isotype	IgG
Formulation	SAE2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	SAE2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	ubiquitin like modifier activating enzyme 2
Database Link	NP_005490 Entrez Gene 10054 Human UniProt ID Q9UBT2
Background	SAE2 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (SUMO-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. This sumoylation is effected by the heterodimeric enzyme SAE1/SAE2 and the SUMO-1-conjugating enzyme Ubch9. The sumoylation pathway mediated by SAE1/SAE2 is distinct from other ubiquitin-like protein (Ubl) pathways.
Synonyms	ARX; HRIHFB2115; SAE2
Reference Data
Protein Pathways	Ubiquitin mediated proteolysis

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