SIK3 Chicken Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Chicken
Clonality	Polyclonal
Immunogen	SIK3 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SIK3.
Formulation	SIK3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	SIK3 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	SIK family kinase 3
Database Link	NP_079440 Entrez Gene 70661 MouseEntrez Gene 684112 RatEntrez Gene 23387 Human UniProt ID Q9Y2K2
Background	SIK3 Antibody: Salt-inducible kinase family (SIKs) proteins are thought to have a role in steroidogenesis, adipogenesis or regulation of tumor malignancy. Three members (SIK1, SIK2 and SIK3) in the SIK family have been identified thus far. Their kinase domain sequences are closely homologous to those of AMP-activated protein kinase (AMPK). SIK3 can be phosphorylated by a tumor-suppressor kinase LKB1. It is highly and preferentially expressed in ovarian tumors but not in adenomyosis and leiomyoma and may be a potential diagnostic marker for ovarian cancers.
Synonyms	L19; QSK; SIK-3
Reference Data
Protein Families	Druggable Genome, Protein Kinase

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