RBM35A (ESRP1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 0.5 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	RBM35A antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human RBM35A.
Isotype	IgG
Formulation	RBM35A Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	RBM35A Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	epithelial splicing regulatory protein 1
Database Link	NP_001030087 Entrez Gene 207920 MouseEntrez Gene 500409 RatEntrez Gene 54845 Human UniProt ID Q6NXG1
Background	RBM35A Antibody: RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.
Synonyms	RBM35A; RMB35A
Reference Data

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