Protor 1 (PRR5) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	PRR5 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human PRR5.
Isotype	IgG
Formulation	PRR5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	PRR5 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	proline rich 5
Database Link	NP_851850 Entrez Gene 55615 Human UniProt ID P85299
Background	PRR5 Antibody: Proline-rich protein 5 (PRR5), also known as Protor-1, is a 388 amino acid protein in Protor family, is thought to act as a tumor suppressor in breast and colorectal tumorigenesis. PRR5 is widely expressed and possesses two RICTOR interaction sites and a C-terminal Proline rich region. It promotes Rapamycin complex 2 (mTORC2) activity. There are four isoforms of PRR5 that are produced as a result of alternative splicing events and these isoforms play an important role in the modulation of platelet-derived growth factor signaling and in the regulation of PDGFR-beta expression.
Synonyms	FLJ20185k; PP610; PROTOR-1; PROTOR1
Reference Data

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