NLRP8 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	NALP8 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP8.
Isotype	IgG
Formulation	NALP8 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	NALP8 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	NLR family, pyrin domain containing 8
Database Link	NP_789781 Entrez Gene 126205 Human UniProt ID Q86W28
Background	NALP8 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.
Synonyms	CLR19.2; NALP8; NOD16; PAN4
Reference Data

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