GBP6 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 0.5 ug/mL, IF: 5 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	GBP6 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human GBP6.
Isotype	IgG
Formulation	GBP6 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	GBP6 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Gene Name	guanylate binding protein family member 6
Database Link	NP_940862 Entrez Gene 100702 MouseEntrez Gene 163351 Human UniProt ID Q6ZN66
Background	GBP6 Antibody: The guanylate-binding proteins (GBPs), a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN) (1,3). GBP6 is induced by IFN and hydrolyzes GTP to both GDP and GMP. The precise function of GBP6 is still under investigation.
Synonyms	DKFZp686G0786; FLJ39135
Reference Data

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