EFCAB4A (CRACR2B) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	EFCAB4A antibody was raised against a 15 amino acid synthetic peptide near the center of human EFCAB4A.
Isotype	IgG
Formulation	EFCAB4A Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	EFCAB4A Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	calcium release activated channel regulator 2B
Database Link	NP_775855 Entrez Gene 213573 MouseEntrez Gene 309112 RatEntrez Gene 283229 Human UniProt ID Q8N4Y2
Background	EFCAB4A Antibody: EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
Synonyms	EFCAB4A
Reference Data

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