Cd9 Rat Monoclonal Antibody [Clone ID: eBioKMC8 (KMC8)]
CNY 2,190.00
货期*
4周
规格
经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | eBioKMC8 (KMC8) |
Applications | FC |
Recommend Dilution | Flow, WB |
Reactivity | Mouse |
Host | Rat |
Clonality | Monoclonal |
Formulation | Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer |
Concentration | lot specific |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | CD9 antigen |
Database Link | |
Background | The eBioKMC8 monoclonal antibody reacts with mouse CD9, a 24 kDa member of the transmembrane 4 superfamily. This family is characterized by the presence of four hydrophobic domains spanning the cell membrane and short N- and C-terminal cytoplasmic domains. CD9 is expressed by several cell types including monocytes, macrophages, platelets, early B cells, activated B and T cells, dendritic cells, eosinophils, basophils, endothelial cells, myoblasts and neuroblasts. On T cells, CD9 functions as a co-stimulatory molecule on na?ve T cells. Furthermore, CD9 is expressed in oocytes, and CD9-deficiency results in sterility caused by defective gamete fusion. In mouse macrophages, CD9 functionally associates with FcγRs to modify signals for phagocytosis and inflammatory responses. In mouse B cells, it was discovered that CD9 is a marker for marginal zone B cells, B1 cells, and plasma cells. In dendritic cells, recently it was demonstrated that CD9 facilitates the association of heterologous MHC II molecules. The level of CD9 expression is subject to donor variability. |
Synonyms | 5H9; BA2; BTCC-1; DRAP-27; GIG2; MIC3; MRP-1; OTTHUMP00000041576; P24; Tetraspanin-29; Tspan-29; TSPAN29 |
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