Amylin (IAPP) Rabbit Polyclonal Antibody
CAT＃: TA321122S
Anti-IAPP Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 1280.00
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CNY 300.00
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Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 200-1000 WB positive control: Raji cells |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 40-52 amino acids of Human Islet amyloid polypeptide |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 10 kDa |
| Gene Name | islet amyloid polypeptide |
| Database Link | |
| Background | Islet; or insulinoma; amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II; or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time; a direct causative role for amylin has been harder to establish. Studies suggest that amylin; like the related beta-amyloid (Abeta) associated with Alzheimer's disease; can induce apoptotic cell-death in particular cultured cells; an effect that may be relevant to the development of type II diabetes. |
| Synonyms | DAP; IAP |
| Reference Data | |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Maturity onset diabetes of the young |
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