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Angiotensin II Type 2 Receptor (AGTR2) Rabbit Polyclonal Antibody
CAT＃: TA321179S
Anti-AGTR2 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 25-100 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 349-363 amino acids of human angiotensin II receptor, type 2 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | angiotensin II receptor type 2 |
| Database Link | |
| Background | The protein encoded by this gene belongs to the G-protein coupled receptor 1 family; and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus; but scantily in adult tissues; except brain; adrenal medulla; and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation. |
| Synonyms | AT2; ATGR2; MRX88 |
| Reference Data | |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction, Renin-angiotensin system |
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