ALAS1 Rabbit Polyclonal Antibody
CAT＃: TA321181S
Anti-ALAS1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
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CNY 300.00
CNY 1430.00
CNY 3080.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 15-50 Positive control: Human breast cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to C terminal 219 amino acids of human aminolevulinate, delta-, synthase 1 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | 5'-aminolevulinate synthase 1 |
| Database Link | |
| Background | This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Synonyms | ALAS; ALAS-H; ALAS3; ALASH; MIG4 |
| Reference Data | |
| Protein Pathways | Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin and chlorophyll metabolism |
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