ITGB6 Rabbit Polyclonal Antibody
CAT＃: TA321227S
Anti-ITGB6 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
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CNY 300.00
CNY 1430.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-300 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm and Cell membrane |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 139-434 amino acids of human integrin, beta 6 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | integrin subunit beta 6 |
| Database Link | |
| Background | Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. Integrin; beta 6 has been shown to interact with FHL2. Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. |
| Synonyms | AI1H |
| Reference Data | |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton |
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