Aquaporin 3 (AQP3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human colorectal cancer Predicted cell location: Cell membrane
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 278-292 amino acids of Human Aquaporin-3
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	32 kDa
Gene Name	aquaporin 3 (Gill blood group)
Database Link	NP_004916 Entrez Gene 11828 MouseEntrez Gene 65133 RatEntrez Gene 360 Human UniProt ID Q92482
Background	This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein; also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function; aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol; but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms.
Synonyms	AQP-3; GIL
Reference Data
Protein Families	Druggable Genome, Transmembrane

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