ZNRF1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 200-1000 WB positive control: Hela cells
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 65-86 amino acids of human zinc and ring finger 1, E3 ubiquitin protein ligase
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	24 kDa
Gene Name	zinc and ring finger 1, E3 ubiquitin protein ligase
Database Link	NP_115644 Entrez Gene 170737 MouseEntrez Gene 84937 Human UniProt ID Q8ND25
Background	This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment; indicating that it may be involved in ubiquitin-mediated protein modification; and in synaptic vessicle membranes in neurons.
Synonyms	NIN283
Reference Data
Protein Families	Druggable Genome

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