ZWILCH Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1000-5000 WB positive control: HT-29 and hela cells
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 249-450 amino acids of human zwilch kinetochore protein
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	67 kDa
Gene Name	zwilch kinetochore protein
Database Link	NP_060445 Entrez Gene 68014 MouseEntrez Gene 55055 Human UniProt ID Q9H900
Background	This protein is essential component of the mitotic checkpoint; which prevents cells from prematurely exiting mitosis. And it is required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. ZWILCH gene is deleted in a patient suffering from colorectal cancer with chromosomal instability.
Synonyms	hZwilch; KNTC1AP
Reference Data

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