SOCS7 Rabbit Polyclonal Antibody
CAT＃: TA322370S
Anti-SOCS7 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
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CNY 300.00
CNY 1430.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm, Nucleus |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 6-20 amino acids of human suppressor of cytokine signaling 7 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | suppressor of cytokine signaling 7 |
| Database Link | |
| Background | The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin; growth hormone and leptin signaling by preventing STAT3 and STAT5 activation; sequestering them in the cytoplasm and reducing their binding to DNA. |
| Synonyms | NAP4; NCKAP4 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Jak-STAT signaling pathway |
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