KCNH3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 10-50 Positive control: Human brain Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 95-144 amino acids of Human potassium voltage-gated channel, subfamily H (eag-related), member 3
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	potassium voltage-gated channel subfamily H member 3
Database Link	NP_036416 Entrez Gene 16512 MouseEntrez Gene 27150 RatEntrez Gene 23416 Human UniProt ID Q9ULD8
Background	Potassium voltage-gated channel subfamily H member 3 is a protein that in humans is encoded by the KCNH3 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit. Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP and subunit assembly. The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Detected only in brain; in particular in the telencephalon. Detected in the cerebral cortex; occipital pole; frontal and temporal lobe; putamen; amygdala; hippocampus and caudate nucleus.
Synonyms	BEC1; ELK2; Kv12.2
Reference Data
Protein Families	Druggable Genome, Ion Channels: Potassium, Transmembrane

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