TRF2 (TERF2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 327-340 amino acids of human telomeric repeat binding factor 2
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	telomeric repeat binding factor 2
Database Link	NP_005643 Entrez Gene 7014 Human UniProt ID Q15554
Background	This gene encodes a telomere specific protein; TERF2; which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle; is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization; TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
Synonyms	TRBF2; TRF2
Reference Data
Protein Families	Transcription Factors

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