AKAP12 Rabbit Polyclonal Antibody
CAT＃: TA322669S
Anti-AKAP12 Rabbit Polyclonal Antibody
Size: 100 ul
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Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-200 Positive control: Human brain Predicted cell location: Cytoplasm |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 1768-1782 amino acids of human A kinase (PRKA) anchor protein 12 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | A-kinase anchoring protein 12 |
| Database Link | |
| Background | The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins; which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells; cultured fibroblasts; and osteosarcoma cells. It associates with protein kinases A and C and phosphatase; and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
| Synonyms | AKAP250; SSeCKS |
| Reference Data | |
| Protein Families | Druggable Genome |
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