SEL1L Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human gasrtic cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 561-572 amino acids of human sel-1 suppressor of lin-12-like (C. elegans)
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	SEL1L ERAD E3 ligase adaptor subunit
Database Link	NP_005056 Entrez Gene 20338 MouseEntrez Gene 314352 RatEntrez Gene 6400 Human UniProt ID Q9UBV2
Background	The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol; where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms	PRO1063; SEL1-LIKE; SEL1L1
Reference Data
Protein Families	Druggable Genome, Transmembrane

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