EAAT4 (SLC1A6) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human testis tissue and A375 cells IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 205-220 amino acids of Human Solute carrier family 1 member 6
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	62 kDa
Gene Name	solute carrier family 1 member 6
Database Link	NP_005062 Entrez Gene 20513 MouseEntrez Gene 84012 RatEntrez Gene 6511 Human UniProt ID P48664
Background	Excitatory amino-acid transporter 4 (EAAT4) is a protein that in humans is encoded by the SLC1A6 gene.It is a member of the high-affinity glutamate and neutral amino acid-transporter family. It transports L-glutamate and also L- and D-aspartate predominantly in the cerebellar cortex. Genetic polymorphism in the SLC1A6 gene is suggested to be refered to glutamatergic dysfunction in schizophrenia pathogenesis.
Synonyms	EAAT4
Reference Data
Protein Families	Transmembrane

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