SLC10A1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 15-50 Positive control: Human lung cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 2-15 amino acids of Human solute carrier family 10 (sodium/bile acid cotransporter family), member 1
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	solute carrier family 10 member 1
Database Link	NP_003040 Entrez Gene 20493 MouseEntrez Gene 6554 Human UniProt ID Q14973
Background	The protein encoded by this gene belongs to the sodium/bile acid cotransporter family; which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen; bile duct and kidney; and the liver-specific sodium/bile acid cotransporter; represented by this protein; that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism; hence this protein is important for cholesterol homeostasis.
Synonyms	NTCP
Reference Data
Protein Families	Druggable Genome, Transmembrane

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