IRF1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: NIH/3T3 and Jurkat cells IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide peptide corresponding to a region derived from 220-233 amino acids of human interferon regulatory factor 1
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	37 kDa
Gene Name	interferon regulatory factor 1
Database Link	NP_002189 Entrez Gene 16362 MouseEntrez Gene 24508 RatEntrez Gene 3659 Human UniProt ID P10914
Background	IRF1 encodes interferon regulatory factor 1; a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription; and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha; beta; and gamma. Further; IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.?
Synonyms	IRF-1; MAR
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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