GLP1 (GCG) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 10-50 Positive control: Human breast cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 1-15 amino acids of Human glucagon
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	glucagon
Database Link	NP_002045 Entrez Gene 14526 MouseEntrez Gene 24952 RatEntrez Gene 2641 Human UniProt ID P01275
Background	The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these; glucagon; is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally; the fourth peptide is similar to glicentin; an active enteroglucagon.
Synonyms	GLP1; GLP2; GRPP
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein

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