Orexin (HCRT) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human lung cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 2-15 amino acids of human hypocretin (orexin) neuropeptide precursor
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	hypocretin (orexin) neuropeptide precursor
Database Link	NP_001515 Entrez Gene 15171 MouseEntrez Gene 25723 RatEntrez Gene 3060 Human UniProt ID O43612
Background	This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides; orexin A and orexin B; by proteolytic processing. Orexin A and orexin B; which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2; function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior; metabolism; and homeostasis.
Synonyms	NRCLP1; OX; PPOX
Reference Data
Protein Families	Druggable Genome, Transmembrane

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