TGF alpha (TGFA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 24-98 amino acids of human transforming growth factor, alpha
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	transforming growth factor alpha
Database Link	NP_003227 Entrez Gene 21802 MouseEntrez Gene 24827 RatEntrez Gene 7039 Human UniProt ID P01135
Background	This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor; which activates a signaling pathway for cell proliferation; differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers; and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms	TFGA
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways	ErbB signaling pathway, Glioma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Renal cell carcinoma

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