PEG10 Rabbit Polyclonal Antibody
CAT＃: TA323342S
Anti-PEG10 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 1280.00
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Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 200-1000 WB positive control: 231 and A549 cells |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to C terminal 250 amino acids of human paternally expressed 10 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 80 kDa |
| Gene Name | paternally expressed 10 |
| Database Link | |
| Background | This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs); RF1 and RF1/RF2; as well as retroviral-like slippage and pseudoknot elements; which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants; as well as from use of upstream non-AUG (CUG) start codon; have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. |
| Synonyms | EDR; HB-1; Mar2; Mart2; MEF3L; RGAG3 |
| Reference Data | |
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