PP2A-beta (PPP2CB) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: Jurkat cells IHC: 50-200 Positive control: Human breast cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 292-306 amino acids of Human protein phosphatase 2, catalytic subunit, beta isozyme
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	36 kDa
Gene Name	protein phosphatase 2 catalytic subunit beta
Database Link	NP_001009552 Entrez Gene 19053 MouseEntrez Gene 24673 RatEntrez Gene 5516 Human UniProt ID P62714
Background	This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases; and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme; which is composed of a catalytic subunit and a constant regulatory subunit; that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit.
Synonyms	PP2Abeta; PP2CB
Reference Data
Protein Families	Druggable Genome, Phosphatase
Protein Pathways	Long-term depression, Oocyte meiosis, TGF-beta signaling pathway, Tight junction, Wnt signaling pathway

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