DOK1 Rabbit Polyclonal Antibody
CAT＃: TA324070S
Anti-DOK1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 300.00
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Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Human hepatocellsular carcinoma tissue and Jurkat cells |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to C terminal 300 amino acids of human docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 52 kDa |
| Gene Name | docking protein 1 |
| Database Link | |
| Background | The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. |
| Synonyms | P62DOK |
| Reference Data | |
| Protein Families | Druggable Genome |
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