MMP11 Rabbit Polyclonal Antibody
CAT#: TA324102S
Anti-MMP11 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 3080.00
Specifications
| Product Data | |
| Applications | WB | 
| Recommend Dilution | WB: 500-2000 WB positive control: Human colon and ovarian cancer tissue  | 
        
| Reactivity | Human, Mouse | 
| Host | Rabbit | 
| Clonality | Polyclonal | 
| Immunogen | Synthetic peptide corresponding to a region derived from 470-488 amino acids of Human matrix metallopeptidase 11 (stromelysin 3) | 
| Isotype | IgG | 
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol | 
| Purification | Antigen affinity purification | 
| Conjugation | Unconjugated | 
| Storage Condition | Store at -20°C as received. | 
| Predicted Protein Size | 55 kDa | 
| Gene Name | matrix metallopeptidase 11 | 
| Database Link | |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; and tissue remodeling; as well as in disease processes; such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However; the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's; this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. | 
| Synonyms | SL-3; ST3; STMY3 | 
| Reference Data | |
| Protein Families | Druggable Genome, Protease | 
Documents
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