Caspase 2 (CASP2) Rabbit Polyclonal Antibody
CAT#: TA324170S
Anti-CASP2 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
CNY 300.00
CNY 1430.00
Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 1000-5000 WB positive control: Hela cells |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to N terminal 201 amino acids of Human Caspase-2 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 51 kDa |
| Gene Name | caspase 2 |
| Database Link | |
| Background | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways; cell cycle maintenance; and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease; Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Synonyms | CASP-2; ICH1; NEDD-2; NEDD2; PPP1R57 |
| Reference Data | |
| Protein Families | Druggable Genome, Protease |
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