SPDEF Rabbit Polyclonal Antibody
CAT＃: TA324209S
Anti-SPDEF Rabbit Polyclonal Antibody
Size: 100 ul
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Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-100 Positive control: Human colorectal cancer Predicted cell location: Nucleus |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 129-332 amino acids of human SAM pointed domain containing ets transcription factor |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | SAM pointed domain containing ETS transcription factor |
| Database Link | |
| Background | The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells; and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain; breast; lung and ovarian tumors; compared to the corresponding normal tissues; and it shows better tumor-association than other cancer-associated molecules; making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Synonyms | bA375E1.3; PDEF |
| Reference Data | |
| Protein Families | Transcription Factors |
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