MDC1 Mouse Monoclonal Antibody [Clone ID: P2B11]

Specifications

Product Data
Clone Name	P2B11
Recommend Dilution	WB: 1:2000
Reactivity	Mouse, Human, Chimpanzee, Bovine
Host	Mouse
Clonality	Monoclonal
Immunogen	GST-tagged recombinant protein corresponding to mouse MDC1 ar and around the N-terminus
Isotype	IgG1
Formulation	PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	mediator of DNA damage checkpoint 1
Database Link	NP_055456 Entrez Gene 240087 MouseEntrez Gene 9656 Human UniProt ID Q14676
Background	MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.
Synonyms	NFBD1
Note	Detects ~184kDa. This antibody recognizes MDC1 at and around the N-terminus.
Reference Data

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