Kcnip3 Mouse Monoclonal Antibody [Clone ID: S66-38]

Specifications

Product Data
Clone Name	S66-38
Applications	IHC
Recommend Dilution	WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Fusion protein amino acids 1-256 (Full length) of rat Calsenillin/DREAM/KChIP3
Isotype	IgG2a
Formulation	PBS pH7.4, 50% glycerol
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	potassium voltage-gated channel interacting protein 3
Database Link	NP_115851 Entrez Gene 30818 HumanEntrez Gene 56461 MouseEntrez Gene 65199 Rat UniProt ID Q9JM47
Background	There are four member of the KChiPs (Kv4 potassium channel interacting protein) family. They are all EF handcontaining proteins required for the traffic of channelforming Kv4 K+ subunits to the plasma membrane . KChiP3 is also known as calsenilin and as the transcription factor, downstream regulatory element antagonist modulator (DREAM), which regulates a number of genes including prodynorphon. They are highly expressed in the hippocampus. Through its various functions, it may play a role in the regulation of synaptic plasticity, learning and memory .
Synonyms	calsenilin; CSEN; DREAM; KCHIP3; MGC18289
Note	Detects ~34kDa. No cross reactivity against KCIPs 1,2 or 4
Reference Data

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