PHF14 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	PHF14 antibody was raised against a 19 amino acid peptide near the amino terminus of human PHF14.
Isotype	IgG
Formulation	PHF14 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	PHF14 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 98 kDa; Observed: 100 kDa
Gene Name	PHD finger protein 14
Database Link	NP_055475 Entrez Gene 75725 MouseEntrez Gene 500030 RatEntrez Gene 9678 Human UniProt ID O94880
Background	PHF14, a novel plant homology domain (PHD) transcription factor, controls the proliferation of mesenchymal cells by regulating PDGFR alpha expression in embryonic development (1). PHD finger transcription factors are concerned with transcriptional regulation by interacting with modified histones (2), and dysregulation of several genes encoding PHD finger transcription factors, such as ING1 and RBP2, has been found in human cancer diseases suggesting these factors have an important role for cancer cell proliferation. PHF14 is a potential target for new treatments of lung fibrosis (1, 3).
Synonyms	MGC176640
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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