THAP11 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	THAP11 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human THAP11.
Formulation	THAP11 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	THAP11 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 35 kDa; Observed: 38 kDa
Gene Name	THAP domain containing 11
Database Link	NP_065190 Entrez Gene 59016 MouseEntrez Gene 307806 RatEntrez Gene 57215 Human UniProt ID Q96EK4
Background	The THAP domain-contining protein 11 (THAP11), also known as Ronin, is an essential factor involved in embryonic stem (ES) cell pluripotency and cell growth (1). THAP 11 contains a THAP domain, a conserved DNA-binding domain common to many proteins associated with chromatin modification and gene expression silencing, and has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases (2). THAP11 can also negatively regulate CD44 v6 expression through its interaction with the poly(rC) binding protein PCBP1 (3).
Synonyms	CTG-B43a; CTG-B45d; HRIHFB2206; RONIN
Reference Data

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