H3FT (HIST3H3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ChIP, ChIP-seq, Dot, ELISA, ICC/IF, IHC, WB
Recommend Dilution	WB,1:500 - 1:1000 DB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. ChIP,5μg antibody for 5μg-10μg of Chromatin ChIP-seq,1:20 - 1:100
Reactivity	Human, Mouse, Rat, Other (Wide Range)
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Formulation	Buffer: PBS with 0.09% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	16kDa
Gene Name	histone cluster 3, H3
Database Link	NP_003484 Entrez Gene 691496 RatEntrez Gene 8290 Human UniProt ID Q16695
Background	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Synonyms	g; H3; H3.4; H3FT; H3t
Reference Data
Protein Pathways	Systemic lupus erythematosus

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