PTBP1 Mouse Monoclonal Antibody [Clone ID: 3H7]

Specifications

Product Data
Clone Name	3H7
Applications	IHC, WB
Recommend Dilution	WB, IHC
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human PTBP1 (full length)
Isotype	IgG1, kappa
Formulation	Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Concentration	lot specific
Purification	The antibody was purified by affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	59.6 kD
Gene Name	polypyrimidine tract binding protein 1
Database Link	NP_114367 Entrez Gene 5725 Human UniProt ID P26599
Background	The 3H7 monoclonal antibody recognizes human PTBP1 also known as Polypyrimidine tract binding protein 1, Heterogeneous nuclear ribonucleoprotein I, and 57 kD RNA-binding protein. PTBP1 is a ubiquitously expressed nuclear protein with a predicted molecular weight approximately 59.6 kD. The polypyrimidine tract binding protein (PTB) is an important regulator of alternative splicing that also affects mRNA localization, stabilization, polyadenylation, and translation. PTBP1 has been shown to interact with FUS, Caspase3, PKCa, Raver1, and HnRNP-L protein. The PTB gene contains 15 exons and spans 13.5 kb. The 3H7 antibody has been shown to be useful for Western blotting.
Synonyms	HNRNP-I; HNRNPI; HNRPI; pPTB; PTB; PTB-1; PTB-T; PTB2; PTB3; PTB4
Reference Data
Protein Families	Druggable Genome

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