Cacng2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:200-1:2000; FC: 1:50-1:600
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide (C)RATDYLQASAITRIPS, corresponding to amino acid residues 213-228 of mouse Cav?2. Intracellular, C-terminus.
Formulation	Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Reconstitution Method	Add 50 ul double distilled water (DDW) to the lyophilized powder.
Purification	Affinity purified on immobilized antigen.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	calcium channel, voltage-dependent, gamma subunit 2
Database Link	NP_031609 Entrez Gene 10369 HumanEntrez Gene 84347 RatEntrez Gene 12300 Mouse UniProt ID O88602
Background	The ? subunit protein is an auxiliary subunit of the CaV (voltage dependent calcium) channel multimer complex. ?1 was first identified in skeletal muscle as a part of the proteins complex purified as the DHP receptor. Eight ? subunit isoforms were identified in mammalian genoms and they share some sequence as well as structure homology.1 ? subunit contains four transmembrane helixes, with intracellular N and C termini. Usually their association with the pore-forming a1 subunit results in reduced current amplitude.CaV?2 is also known as stargazin, and interacts and regulates the activity and trafficking of AMPA glutamate receptors.
Synonyms	MGC138502; MGC138504; stargazin
Reference Data

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