P2ry6 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:200-1:2000; IHC: 1:100-1:3,000; FC: 1:50-1:600
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide CQPHDLLQKLTAKWQRQRV, corresponding to amino acid residues 311-328 of rat P2Y6 receptor. Intracellular, C-terminus.
Formulation	Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Reconstitution Method	Add 50 ul double distilled water (DDW) to the lyophilized powder.
Purification	Affinity purified on immobilized antigen.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	pyrimidinergic receptor P2Y6
Database Link	NP_476465 Entrez Gene 5031 HumanEntrez Gene 233571 MouseEntrez Gene 117264 Rat UniProt ID Q63371
Background	The nucleotide receptor P2Y6 binds UDP, and is a member of the G-protein coupled receptor superfamily. P2Y6 agonists induce an inositol phosphate/Ca2+ response that is insensitive to pertussis toxin inhibition. P2Y6 is coupled to phospholipase C via Gq, and is also coupled to inhibition of N-type Ca2+ and M-type K+ channels. P2Y6 mRNA is expressed in various rat tissues, including lung, stomach, intestine, spleen, heart, and aorta. P2Y6 was reported to mediate contractions in human cerebral arteries. Alomone Labs is please to offer a highly specific antibody directed against the C-terminus domain of the rat P2Y6 receptor. Anti-P2Y6 Receptor antibody can be used in western blot analysis, indirect flow cytometry, immunoprecipitation, immunocytochemistry and immunohistochemistry. It has been designed to recognize P2Y6 from rat, mouse and human samples.
Synonyms	MGC15335; P2Y6
Reference Data

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