DENND1C Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for Anti-DENND1C Antibody is: synthetic peptide directed towards the C-terminal region of Human DENND1C. Synthetic peptide located within the following region: PSSLEDPRARPPKALLAERAHLQPREEPGALNSPATPTSNCQKSQPSSRP
Isotype	IgG
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	87 kDa
Gene Name	DENN domain containing 1C
Database Link	NP_079174 Entrez Gene 79958 Human UniProt ID Q8IV53
Background	Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.
Synonyms	FAM31C
Note	Immunogen sequence homology: Human: 100%
Reference Data

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